• Investing
  • Stock
  • Editor’s Pick
  • Economy
The Significant Deals
Stock

US FDA puts Kezar Life Sciences’ lupus treatment trial on hold after patient deaths

by October 4, 2024
written by October 4, 2024

(Reuters) -The U.S. Food and Drug Administration has placed a clinical hold on Kezar Life Sciences (NASDAQ:KZR)’ trial of experimental drug for lupus, the company said on Friday.

The FDA’s decision comes after the company said it had paused the mid-stage trial of the drug, zetomipzomib, to review safety data following the deaths of four patients, who were part of the trial in the Philippines and Argentina.

Kezar was testing the drug in patients with active lupus nephritis, which causes inflammation and damage in the kidneys due to a form of immune-related condition called lupus.

An independent study committee had recommended a pause on the trial, after it found that three of the fatalities showed a common pattern of symptoms and the deaths happened close to the time of dosing, while a non-fatal adverse event also showed a similar proximity to the dosing time.

The company said that a separate mid-stage trial testing zetomipzomib in patients with autoimmune hepatitis remains active and no serious adverse events have been reported so far.

This post appeared first on investing.com
0 comment
0
FacebookTwitterPinterestEmail

previous post
Mexico stocks higher at close of trade; S&P/BMV IPC up 1.81%
next post
Citron’s Andrew Left asks judge to dismiss SEC’s fraud case

You may also like

BASF results down on impairments, restructuring

January 27, 2025

European chipmakers slump as traders gauge DeepSeek AI...

January 27, 2025

Nasdaq futures tumble as China’s AI push rattles...

January 27, 2025

China Vanke’s CEO, chairman resign amid growing liquidity...

January 27, 2025

Fuji Media, rocked by sexual misconduct allegations, says...

January 27, 2025

Italy’s MPS shares fall ahead of Mediobanca board...

January 27, 2025

British Land stock drops following stake sale

January 27, 2025

UMG shares rally after new multi-year pact with...

January 27, 2025

BASF shares indicated 3% lower as impairments drag...

January 27, 2025

Ryanair cuts 2026 traffic forecast amid ongoing Boeing...

January 27, 2025
Fill Out & Get More Relevant News








    Stay ahead of the market and unlock exclusive trading insights & timely news. We value your privacy - your information is secure, and you can unsubscribe anytime. Gain an edge with hand-picked trading opportunities, stay informed with market-moving updates, and learn from expert tips & strategies.

    Recent Posts

    • Trump implies government could cut contracts and subsidies to Musk’s companies

      June 7, 2025
    • Procter & Gamble to cut 7,000 jobs as part of broader restructuring

      June 6, 2025
    • Shein and Temu see U.S. demand plunge as loophole for cheap goods closes

      June 6, 2025
    • Shein and Temu see U.S. demand plunge as loophole for cheap goods closes

      June 5, 2025

    Categories

    • Economy (245)
    • Editor's Pick (3,646)
    • Investing (505)
    • Stock (6,426)

    Latest News

    • Trump implies government could cut contracts and subsidies to Musk’s companies
    • Procter & Gamble to cut 7,000 jobs as part of broader restructuring

    Popular News

    • Nvidia, United Health lead market cap stock movers on Monday
    • Asian stocks climb on Wall Street lead; yuan, euro sag

    About The Significant deals

    • Privacy Policy
    • Terms & Conditions

    Copyright © 2025 thesignificantdeals.com | All Rights Reserved

    The Significant Deals
    • Investing
    • Stock
    • Editor’s Pick
    • Economy